{"id":15,"date":"2021-11-21T15:14:41","date_gmt":"2021-11-21T15:14:41","guid":{"rendered":"https:\/\/joanabpereiralab.com\/index.php\/services\/"},"modified":"2023-12-11T17:03:24","modified_gmt":"2023-12-11T16:03:24","slug":"research","status":"publish","type":"page","link":"https:\/\/joanabpereiralab.com\/index.php\/research\/","title":{"rendered":"RESEARCH"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"15\" class=\"elementor elementor-15\" data-elementor-post-type=\"page\">\n\t\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-83746e8 elementor-section-height-min-height elementor-section-boxed elementor-section-height-default elementor-section-items-middle\" data-id=\"83746e8\" data-element_type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;shape_divider_bottom&quot;:&quot;tilt&quot;}\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t<div class=\"elementor-shape elementor-shape-bottom\" data-negative=\"false\">\n\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 1000 100\" preserveAspectRatio=\"none\">\n\t<path class=\"elementor-shape-fill\" d=\"M0,6V0h1000v100L0,6z\"\/>\n<\/svg>\t\t<\/div>\n\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-09faee3\" data-id=\"09faee3\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-c7152a9 elementor-widget elementor-widget-heading\" data-id=\"c7152a9\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.18.0 - 04-12-2023 *\/\n.elementor-heading-title{padding:0;margin:0;line-height:1}.elementor-widget-heading .elementor-heading-title[class*=elementor-size-]>a{color:inherit;font-size:inherit;line-height:inherit}.elementor-widget-heading .elementor-heading-title.elementor-size-small{font-size:15px}.elementor-widget-heading .elementor-heading-title.elementor-size-medium{font-size:19px}.elementor-widget-heading .elementor-heading-title.elementor-size-large{font-size:29px}.elementor-widget-heading .elementor-heading-title.elementor-size-xl{font-size:39px}.elementor-widget-heading .elementor-heading-title.elementor-size-xxl{font-size:59px}<\/style><h1 class=\"elementor-heading-title elementor-size-default\">OUR RESEARCH<\/h1>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t<div class=\"elementor-element elementor-element-ade70a5 e-con-full elementor-hidden-desktop elementor-hidden-mobile e-flex e-con e-parent\" data-id=\"ade70a5\" data-element_type=\"container\" data-settings=\"{&quot;content_width&quot;:&quot;full&quot;}\" data-core-v316-plus=\"true\">\n\t\t<div class=\"elementor-element elementor-element-84f65a9 e-con-full e-flex e-con e-child\" data-id=\"84f65a9\" data-element_type=\"container\" data-settings=\"{&quot;content_width&quot;:&quot;full&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-7e81730 elementor-widget__width-initial elementor-widget elementor-widget-heading\" data-id=\"7e81730\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">OUR LINES<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-6f7a581 e-con-full e-flex e-con e-child\" data-id=\"6f7a581\" data-element_type=\"container\" data-settings=\"{&quot;content_width&quot;:&quot;full&quot;,&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-09b4cc2 elementor-tabs-view-horizontal elementor-widget elementor-widget-tabs\" data-id=\"09b4cc2\" data-element_type=\"widget\" data-widget_type=\"tabs.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.18.0 - 04-12-2023 *\/\n.elementor-widget-tabs.elementor-tabs-view-vertical .elementor-tabs-wrapper{width:25%;flex-shrink:0}.elementor-widget-tabs.elementor-tabs-view-vertical .elementor-tab-desktop-title.elementor-active{border-right-style:none}.elementor-widget-tabs.elementor-tabs-view-vertical .elementor-tab-desktop-title.elementor-active:after,.elementor-widget-tabs.elementor-tabs-view-vertical .elementor-tab-desktop-title.elementor-active:before{height:999em;width:0;right:0;border-right-style:solid}.elementor-widget-tabs.elementor-tabs-view-vertical .elementor-tab-desktop-title.elementor-active:before{top:0;transform:translateY(-100%)}.elementor-widget-tabs.elementor-tabs-view-vertical .elementor-tab-desktop-title.elementor-active:after{top:100%}.elementor-widget-tabs.elementor-tabs-view-horizontal .elementor-tab-desktop-title{display:table-cell}.elementor-widget-tabs.elementor-tabs-view-horizontal .elementor-tab-desktop-title.elementor-active{border-bottom-style:none}.elementor-widget-tabs.elementor-tabs-view-horizontal .elementor-tab-desktop-title.elementor-active:after,.elementor-widget-tabs.elementor-tabs-view-horizontal .elementor-tab-desktop-title.elementor-active:before{bottom:0;height:0;width:999em;border-bottom-style:solid}.elementor-widget-tabs.elementor-tabs-view-horizontal .elementor-tab-desktop-title.elementor-active:before{right:100%}.elementor-widget-tabs.elementor-tabs-view-horizontal .elementor-tab-desktop-title.elementor-active:after{left:100%}.elementor-widget-tabs .elementor-tab-content,.elementor-widget-tabs .elementor-tab-title,.elementor-widget-tabs .elementor-tab-title:after,.elementor-widget-tabs .elementor-tab-title:before,.elementor-widget-tabs .elementor-tabs-content-wrapper{border:1px #d5d8dc}.elementor-widget-tabs .elementor-tabs{text-align:left}.elementor-widget-tabs .elementor-tabs-wrapper{overflow:hidden}.elementor-widget-tabs .elementor-tab-title{cursor:pointer;outline:var(--focus-outline,none)}.elementor-widget-tabs .elementor-tab-desktop-title{position:relative;padding:20px 25px;font-weight:700;line-height:1;border:solid transparent}.elementor-widget-tabs .elementor-tab-desktop-title.elementor-active{border-color:#d5d8dc}.elementor-widget-tabs .elementor-tab-desktop-title.elementor-active:after,.elementor-widget-tabs .elementor-tab-desktop-title.elementor-active:before{display:block;content:\"\";position:absolute}.elementor-widget-tabs .elementor-tab-desktop-title:focus-visible{border:1px solid #000}.elementor-widget-tabs .elementor-tab-mobile-title{padding:10px;cursor:pointer}.elementor-widget-tabs .elementor-tab-content{padding:20px;display:none}@media (max-width:767px){.elementor-tabs .elementor-tab-content,.elementor-tabs .elementor-tab-title{border-style:solid solid none}.elementor-tabs .elementor-tabs-wrapper{display:none}.elementor-tabs .elementor-tabs-content-wrapper{border-bottom-style:solid}.elementor-tabs .elementor-tab-content{padding:10px}}@media (min-width:768px){.elementor-widget-tabs.elementor-tabs-view-vertical .elementor-tabs{display:flex}.elementor-widget-tabs.elementor-tabs-view-vertical .elementor-tabs-wrapper{flex-direction:column}.elementor-widget-tabs.elementor-tabs-view-vertical .elementor-tabs-content-wrapper{flex-grow:1;border-style:solid solid solid none}.elementor-widget-tabs.elementor-tabs-view-horizontal .elementor-tab-content{border-style:none solid solid}.elementor-widget-tabs.elementor-tabs-alignment-center .elementor-tabs-wrapper,.elementor-widget-tabs.elementor-tabs-alignment-end .elementor-tabs-wrapper,.elementor-widget-tabs.elementor-tabs-alignment-stretch .elementor-tabs-wrapper{display:flex}.elementor-widget-tabs.elementor-tabs-alignment-center .elementor-tabs-wrapper{justify-content:center}.elementor-widget-tabs.elementor-tabs-alignment-end .elementor-tabs-wrapper{justify-content:flex-end}.elementor-widget-tabs.elementor-tabs-alignment-stretch.elementor-tabs-view-horizontal .elementor-tab-title{width:100%}.elementor-widget-tabs.elementor-tabs-alignment-stretch.elementor-tabs-view-vertical .elementor-tab-title{height:100%}.elementor-tabs .elementor-tab-mobile-title{display:none}}<\/style>\t\t<div class=\"elementor-tabs\">\n\t\t\t<div class=\"elementor-tabs-wrapper\" role=\"tablist\" >\n\t\t\t\t\t\t\t\t\t<div id=\"elementor-tab-title-1011\" class=\"elementor-tab-title elementor-tab-desktop-title\" aria-selected=\"true\" data-tab=\"1\" role=\"tab\" tabindex=\"0\" aria-controls=\"elementor-tab-content-1011\" aria-expanded=\"false\">Brain Aging<\/div>\n\t\t\t\t\t\t\t\t\t<div id=\"elementor-tab-title-1012\" class=\"elementor-tab-title elementor-tab-desktop-title\" aria-selected=\"false\" data-tab=\"2\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-1012\" aria-expanded=\"false\">Neurodegenerative disorders<\/div>\n\t\t\t\t\t\t\t\t\t<div id=\"elementor-tab-title-1013\" class=\"elementor-tab-title elementor-tab-desktop-title\" aria-selected=\"false\" data-tab=\"3\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-1013\" aria-expanded=\"false\">Psychiatric disorders<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t<div class=\"elementor-tabs-content-wrapper\" role=\"tablist\" aria-orientation=\"vertical\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-tab-title elementor-tab-mobile-title\" aria-selected=\"true\" data-tab=\"1\" role=\"tab\" tabindex=\"0\" aria-controls=\"elementor-tab-content-1011\" aria-expanded=\"false\">Brain Aging<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-1011\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"1\" role=\"tabpanel\" aria-labelledby=\"elementor-tab-title-1011\" tabindex=\"0\" hidden=\"false\"><p>Aging is one of the strongest risk factors for the development of neurodegenerative disorders. Our aim is to understand the physiological processes that occur over the the course of aging that hold important clues regarding why some individuals develop a neurodegenerative disease.<\/p><\/div>\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-tab-title elementor-tab-mobile-title\" aria-selected=\"false\" data-tab=\"2\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-1012\" aria-expanded=\"false\">Neurodegenerative disorders<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-1012\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"2\" role=\"tabpanel\" aria-labelledby=\"elementor-tab-title-1012\" tabindex=\"0\" hidden=\"hidden\"><p>Neurodegenerative diseases, such as Alzheimer&#8217;s and Parkinson&#8217;s, often exhibit a protracted preclinical phase, where subtle changes occur years before the onset of overt symptoms. Recognizing the critical window of opportunity during this preclinical stage, our research aims to identify the earliest signs of these disorders through comprehensive imaging and biofluid biomarker analysis. By capturing the initial molecular and structural alterations that precede clinical manifestations, we aim to pave the way for preventive interventions.<\/p><\/div>\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-tab-title elementor-tab-mobile-title\" aria-selected=\"false\" data-tab=\"3\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-1013\" aria-expanded=\"false\">Psychiatric disorders<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-1013\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"3\" role=\"tabpanel\" aria-labelledby=\"elementor-tab-title-1013\" tabindex=\"0\" hidden=\"hidden\"><p>We are interested in the brain alterations occurring in cognitively normal individuals with psychiatric symptoms and patients that have been diagnosed with a psychiatric disorder such as schizophrenia, bipolar disorder, amongst many others.<\/p><\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-751a621 e-con-full elementor-hidden-tablet e-flex e-con e-parent\" data-id=\"751a621\" data-element_type=\"container\" data-settings=\"{&quot;content_width&quot;:&quot;full&quot;}\" data-core-v316-plus=\"true\">\n\t\t<div class=\"elementor-element elementor-element-ab8459c e-con-full elementor-hidden-tablet elementor-hidden-mobile e-flex e-con e-child\" data-id=\"ab8459c\" data-element_type=\"container\" data-settings=\"{&quot;content_width&quot;:&quot;full&quot;,&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-dbb2320 e-con-full e-flex e-con e-child\" data-id=\"dbb2320\" data-element_type=\"container\" data-settings=\"{&quot;content_width&quot;:&quot;full&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-ba63f39 elementor-widget__width-initial elementor-widget elementor-widget-heading\" data-id=\"ba63f39\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">OUR LINES<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-8151dfc e-con-full elementor-hidden-desktop elementor-hidden-tablet e-flex e-con e-child\" data-id=\"8151dfc\" data-element_type=\"container\" data-settings=\"{&quot;content_width&quot;:&quot;full&quot;,&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-dd35ffc elementor-tabs-view-horizontal elementor-widget elementor-widget-tabs\" data-id=\"dd35ffc\" data-element_type=\"widget\" data-widget_type=\"tabs.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-tabs\">\n\t\t\t<div class=\"elementor-tabs-wrapper\" role=\"tablist\" >\n\t\t\t\t\t\t\t\t\t<div id=\"elementor-tab-title-2311\" class=\"elementor-tab-title elementor-tab-desktop-title\" aria-selected=\"true\" data-tab=\"1\" role=\"tab\" tabindex=\"0\" aria-controls=\"elementor-tab-content-2311\" aria-expanded=\"false\">Brain Aging<\/div>\n\t\t\t\t\t\t\t\t\t<div id=\"elementor-tab-title-2312\" class=\"elementor-tab-title elementor-tab-desktop-title\" aria-selected=\"false\" data-tab=\"2\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-2312\" aria-expanded=\"false\">Neurodegenerative disorders<\/div>\n\t\t\t\t\t\t\t\t\t<div id=\"elementor-tab-title-2313\" class=\"elementor-tab-title elementor-tab-desktop-title\" aria-selected=\"false\" data-tab=\"3\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-2313\" aria-expanded=\"false\">Psychiatric disorders<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t<div class=\"elementor-tabs-content-wrapper\" role=\"tablist\" aria-orientation=\"vertical\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-tab-title elementor-tab-mobile-title\" aria-selected=\"true\" data-tab=\"1\" role=\"tab\" tabindex=\"0\" aria-controls=\"elementor-tab-content-2311\" aria-expanded=\"false\">Brain Aging<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-2311\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"1\" role=\"tabpanel\" aria-labelledby=\"elementor-tab-title-2311\" tabindex=\"0\" hidden=\"false\"><p>Aging is one of the strongest risk factors for the development of neurodegenerative disorders. Our aim is to understand the physiological processes that occur over the the course of aging that hold important clues regarding why some individuals develop a neurodegenerative disease.<\/p><\/div>\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-tab-title elementor-tab-mobile-title\" aria-selected=\"false\" data-tab=\"2\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-2312\" aria-expanded=\"false\">Neurodegenerative disorders<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-2312\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"2\" role=\"tabpanel\" aria-labelledby=\"elementor-tab-title-2312\" tabindex=\"0\" hidden=\"hidden\"><p>Neurodegenerative diseases, such as Alzheimer&#8217;s and Parkinson&#8217;s, often exhibit a protracted preclinical phase, where subtle changes occur years before the onset of overt symptoms. Recognizing the critical window of opportunity during this preclinical stage, our research aims to identify the earliest signs of these disorders through comprehensive imaging and biofluid biomarker analysis. By capturing the initial molecular and structural alterations that precede clinical manifestations, we aim to pave the way for preventive interventions.<\/p><\/div>\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-tab-title elementor-tab-mobile-title\" aria-selected=\"false\" data-tab=\"3\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-2313\" aria-expanded=\"false\">Psychiatric disorders<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-2313\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"3\" role=\"tabpanel\" aria-labelledby=\"elementor-tab-title-2313\" tabindex=\"0\" hidden=\"hidden\"><p>We are interested in the brain alterations occurring in cognitively normal individuals with psychiatric symptoms and patients that have been diagnosed with a psychiatric disorder such as schizophrenia, bipolar disorder, amongst many others.<\/p><\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-0b0375c e-con-full elementor-hidden-desktop elementor-hidden-mobile e-flex e-con e-parent\" data-id=\"0b0375c\" data-element_type=\"container\" data-settings=\"{&quot;content_width&quot;:&quot;full&quot;}\" data-core-v316-plus=\"true\">\n\t\t<div class=\"elementor-element elementor-element-e067c97 e-con-full e-flex e-con e-child\" data-id=\"e067c97\" data-element_type=\"container\" data-settings=\"{&quot;content_width&quot;:&quot;full&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-5701c7c elementor-widget__width-initial elementor-widget elementor-widget-heading\" data-id=\"5701c7c\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">brain <br> connectivity<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-13f20bb e-con-full e-flex e-con e-child\" data-id=\"13f20bb\" data-element_type=\"container\" data-settings=\"{&quot;content_width&quot;:&quot;full&quot;,&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5065edc elementor-tabs-view-horizontal elementor-widget elementor-widget-tabs\" data-id=\"5065edc\" data-element_type=\"widget\" data-widget_type=\"tabs.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-tabs\">\n\t\t\t<div class=\"elementor-tabs-wrapper\" role=\"tablist\" >\n\t\t\t\t\t\t\t\t\t<div id=\"elementor-tab-title-8431\" class=\"elementor-tab-title elementor-tab-desktop-title\" aria-selected=\"true\" data-tab=\"1\" role=\"tab\" tabindex=\"0\" aria-controls=\"elementor-tab-content-8431\" aria-expanded=\"false\">Dynamic brain connectivity<\/div>\n\t\t\t\t\t\t\t\t\t<div id=\"elementor-tab-title-8432\" class=\"elementor-tab-title elementor-tab-desktop-title\" aria-selected=\"false\" data-tab=\"2\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-8432\" aria-expanded=\"false\">Multilayer brain connectivity<\/div>\n\t\t\t\t\t\t\t\t\t<div id=\"elementor-tab-title-8433\" class=\"elementor-tab-title elementor-tab-desktop-title\" aria-selected=\"false\" data-tab=\"3\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-8433\" aria-expanded=\"false\">Deep learning for brain connectivity <\/div>\n\t\t\t\t\t\t\t\t\t<div id=\"elementor-tab-title-8434\" class=\"elementor-tab-title elementor-tab-desktop-title\" aria-selected=\"false\" data-tab=\"4\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-8434\" aria-expanded=\"false\">Functional gradients<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t<div class=\"elementor-tabs-content-wrapper\" role=\"tablist\" aria-orientation=\"vertical\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-tab-title elementor-tab-mobile-title\" aria-selected=\"true\" data-tab=\"1\" role=\"tab\" tabindex=\"0\" aria-controls=\"elementor-tab-content-8431\" aria-expanded=\"false\">Dynamic brain connectivity<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-8431\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"1\" role=\"tabpanel\" aria-labelledby=\"elementor-tab-title-8431\" tabindex=\"0\" hidden=\"false\"><p>We have developed a new method to assess dynamic changes in functional brain connectivity that takes into account that there are temporal delays between the activation of different brain regions. This method has proven to be more sensitive to changes occurring in the networks of older adults as well as patients with Parkinson\u2019s disease and Alzheimer\u2019s disease compared to other dynamic connectivity measures.<\/p><\/div>\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-tab-title elementor-tab-mobile-title\" aria-selected=\"false\" data-tab=\"2\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-8432\" aria-expanded=\"false\">Multilayer brain connectivity<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-8432\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"2\" role=\"tabpanel\" aria-labelledby=\"elementor-tab-title-8432\" tabindex=\"0\" hidden=\"hidden\"><p>We have developed a framework to integrate the information from different neuroimaging modalities (DTI, fMRI, PET, T1-w, MEG, EEG, etc) as separate layers into a multilayer brain connectome. This approach allows assessing\u00a0 the interaction between different physiological processes and how this interaction might reveal unique information about different diseases.<\/p><\/div>\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-tab-title elementor-tab-mobile-title\" aria-selected=\"false\" data-tab=\"3\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-8433\" aria-expanded=\"false\">Deep learning for brain connectivity <\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-8433\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"3\" role=\"tabpanel\" aria-labelledby=\"elementor-tab-title-8433\" tabindex=\"0\" hidden=\"hidden\"><p>We are working with different types of neural network architectures such as convolutional neural networks, graph neural networks, transformers or variational autencoders to distinguish subtle changes in Alzheimer\u2019s disease and other disorders using different imaging modalities, biofluid markers and clinical data.<\/p><\/div>\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-tab-title elementor-tab-mobile-title\" aria-selected=\"false\" data-tab=\"4\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-8434\" aria-expanded=\"false\">Functional gradients<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-8434\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"4\" role=\"tabpanel\" aria-labelledby=\"elementor-tab-title-8434\" tabindex=\"0\" hidden=\"hidden\"><p>We employ a gradient-based analytical framework to quantify the topographic principles of macroscale brain organization in aging and its perturbations in neurodegenerative disease. This promotes our understanding of how the functional topography of the human brain changes over aging and in neurodegenerative conditions.<\/p><\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-4e8f63e e-con-full elementor-hidden-tablet e-flex e-con e-parent\" data-id=\"4e8f63e\" data-element_type=\"container\" data-settings=\"{&quot;content_width&quot;:&quot;full&quot;}\" data-core-v316-plus=\"true\">\n\t\t<div class=\"elementor-element elementor-element-6c0bf3e e-con-full elementor-hidden-tablet elementor-hidden-mobile e-flex e-con e-child\" data-id=\"6c0bf3e\" data-element_type=\"container\" data-settings=\"{&quot;content_width&quot;:&quot;full&quot;,&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-35ed0fb e-con-full e-flex e-con e-child\" data-id=\"35ed0fb\" data-element_type=\"container\" data-settings=\"{&quot;content_width&quot;:&quot;full&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-db6bff0 elementor-widget__width-initial elementor-widget elementor-widget-heading\" data-id=\"db6bff0\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">brain <br> connectivity<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-0cade7c e-con-full elementor-hidden-desktop elementor-hidden-tablet e-flex e-con e-child\" data-id=\"0cade7c\" data-element_type=\"container\" data-settings=\"{&quot;content_width&quot;:&quot;full&quot;,&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c1dbc82 elementor-tabs-view-horizontal elementor-widget elementor-widget-tabs\" data-id=\"c1dbc82\" data-element_type=\"widget\" data-widget_type=\"tabs.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-tabs\">\n\t\t\t<div class=\"elementor-tabs-wrapper\" role=\"tablist\" >\n\t\t\t\t\t\t\t\t\t<div id=\"elementor-tab-title-2031\" class=\"elementor-tab-title elementor-tab-desktop-title\" aria-selected=\"true\" data-tab=\"1\" role=\"tab\" tabindex=\"0\" aria-controls=\"elementor-tab-content-2031\" aria-expanded=\"false\">Dynamic brain connectivity<\/div>\n\t\t\t\t\t\t\t\t\t<div id=\"elementor-tab-title-2032\" class=\"elementor-tab-title elementor-tab-desktop-title\" aria-selected=\"false\" data-tab=\"2\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-2032\" aria-expanded=\"false\">Multilayer brain connectivity<\/div>\n\t\t\t\t\t\t\t\t\t<div id=\"elementor-tab-title-2033\" class=\"elementor-tab-title elementor-tab-desktop-title\" aria-selected=\"false\" data-tab=\"3\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-2033\" aria-expanded=\"false\">Deep learning for brain connectivity <\/div>\n\t\t\t\t\t\t\t\t\t<div id=\"elementor-tab-title-2034\" class=\"elementor-tab-title elementor-tab-desktop-title\" aria-selected=\"false\" data-tab=\"4\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-2034\" aria-expanded=\"false\">Functional gradients<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t<div class=\"elementor-tabs-content-wrapper\" role=\"tablist\" aria-orientation=\"vertical\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-tab-title elementor-tab-mobile-title\" aria-selected=\"true\" data-tab=\"1\" role=\"tab\" tabindex=\"0\" aria-controls=\"elementor-tab-content-2031\" aria-expanded=\"false\">Dynamic brain connectivity<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-2031\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"1\" role=\"tabpanel\" aria-labelledby=\"elementor-tab-title-2031\" tabindex=\"0\" hidden=\"false\"><p>We have developed a new method to assess dynamic changes in functional brain connectivity that takes into account that there are temporal delays between the activation of different brain regions. This method has proven to be more sensitive to changes occurring in the networks of older adults as well as patients with Parkinson\u2019s disease and Alzheimer\u2019s disease compared to other dynamic connectivity measures.<\/p><\/div>\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-tab-title elementor-tab-mobile-title\" aria-selected=\"false\" data-tab=\"2\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-2032\" aria-expanded=\"false\">Multilayer brain connectivity<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-2032\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"2\" role=\"tabpanel\" aria-labelledby=\"elementor-tab-title-2032\" tabindex=\"0\" hidden=\"hidden\"><p>We have developed a framework to integrate the information from different neuroimaging modalities (DTI, fMRI, PET, T1-w, MEG, EEG, etc) as separate layers into a multilayer brain connectome. This approach allows assessing\u00a0 the interaction between different physiological processes and how this interaction might reveal unique information about different diseases.<\/p><\/div>\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-tab-title elementor-tab-mobile-title\" aria-selected=\"false\" data-tab=\"3\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-2033\" aria-expanded=\"false\">Deep learning for brain connectivity <\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-2033\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"3\" role=\"tabpanel\" aria-labelledby=\"elementor-tab-title-2033\" tabindex=\"0\" hidden=\"hidden\"><p>We are working with different types of neural network architectures such as convolutional neural networks, graph neural networks, transformers or variational autencoders to distinguish subtle changes in Alzheimer\u2019s disease and other disorders using different imaging modalities, biofluid markers and clinical data.<\/p><\/div>\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-tab-title elementor-tab-mobile-title\" aria-selected=\"false\" data-tab=\"4\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-2034\" aria-expanded=\"false\">Functional gradients<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-2034\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"4\" role=\"tabpanel\" aria-labelledby=\"elementor-tab-title-2034\" tabindex=\"0\" hidden=\"hidden\"><p>We employ a gradient-based analytical framework to quantify the topographic principles of macroscale brain organization in aging and its perturbations in neurodegenerative disease. This promotes our understanding of how the functional topography of the human brain changes over aging and in neurodegenerative conditions.<\/p><\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-c48ee2e e-con-full elementor-hidden-desktop elementor-hidden-mobile e-flex e-con e-parent\" data-id=\"c48ee2e\" data-element_type=\"container\" data-settings=\"{&quot;content_width&quot;:&quot;full&quot;}\" data-core-v316-plus=\"true\">\n\t\t<div class=\"elementor-element elementor-element-c8d2fd5 e-con-full e-flex e-con e-child\" data-id=\"c8d2fd5\" data-element_type=\"container\" data-settings=\"{&quot;content_width&quot;:&quot;full&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4768305 elementor-widget__width-initial elementor-widget elementor-widget-heading\" data-id=\"4768305\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Molecular <br> biomarkers<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-a57f1b2 e-con-full elementor-hidden-desktop e-flex e-con e-child\" data-id=\"a57f1b2\" data-element_type=\"container\" data-settings=\"{&quot;content_width&quot;:&quot;full&quot;,&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c19daa9 elementor-tabs-view-horizontal elementor-widget elementor-widget-tabs\" data-id=\"c19daa9\" data-element_type=\"widget\" data-widget_type=\"tabs.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-tabs\">\n\t\t\t<div class=\"elementor-tabs-wrapper\" role=\"tablist\" >\n\t\t\t\t\t\t\t\t\t<div id=\"elementor-tab-title-2031\" class=\"elementor-tab-title elementor-tab-desktop-title\" aria-selected=\"true\" data-tab=\"1\" role=\"tab\" tabindex=\"0\" aria-controls=\"elementor-tab-content-2031\" aria-expanded=\"false\">PET<\/div>\n\t\t\t\t\t\t\t\t\t<div id=\"elementor-tab-title-2032\" class=\"elementor-tab-title elementor-tab-desktop-title\" aria-selected=\"false\" data-tab=\"2\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-2032\" aria-expanded=\"false\">Biofluid markers<\/div>\n\t\t\t\t\t\t\t\t\t<div id=\"elementor-tab-title-2033\" class=\"elementor-tab-title elementor-tab-desktop-title\" aria-selected=\"false\" data-tab=\"3\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-2033\" aria-expanded=\"false\">Omics<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t<div class=\"elementor-tabs-content-wrapper\" role=\"tablist\" aria-orientation=\"vertical\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-tab-title elementor-tab-mobile-title\" aria-selected=\"true\" data-tab=\"1\" role=\"tab\" tabindex=\"0\" aria-controls=\"elementor-tab-content-2031\" aria-expanded=\"false\">PET<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-2031\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"1\" role=\"tabpanel\" aria-labelledby=\"elementor-tab-title-2031\" tabindex=\"0\" hidden=\"false\"><p>We are working with different PET tracers that quantify amyloid and tau burden as well as glucose metabolism in the brain.<\/p><\/div>\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-tab-title elementor-tab-mobile-title\" aria-selected=\"false\" data-tab=\"2\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-2032\" aria-expanded=\"false\">Biofluid markers<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-2032\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"2\" role=\"tabpanel\" aria-labelledby=\"elementor-tab-title-2032\" tabindex=\"0\" hidden=\"hidden\"><p>We analyze many different biomarkers of Alzheimer&#8217;s and Lewy Body diseases, neurodegeneration, neuroinflammation and synaptic dysfunction. These biomarkers are derived from the analysis of the cerebrospinal fluid and blood plasma.<\/p><\/div>\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-tab-title elementor-tab-mobile-title\" aria-selected=\"false\" data-tab=\"3\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-2033\" aria-expanded=\"false\">Omics<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-2033\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"3\" role=\"tabpanel\" aria-labelledby=\"elementor-tab-title-2033\" tabindex=\"0\" hidden=\"hidden\"><p>We conduct transcriptomic association analyses to relate brain connectome properties with the transcriptomic profiles of specific genes. This allows us to understand the genetic contribution to different connectivity patterns.<\/p><\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-e3ab355 e-con-full elementor-hidden-tablet e-flex e-con e-parent\" data-id=\"e3ab355\" data-element_type=\"container\" data-settings=\"{&quot;content_width&quot;:&quot;full&quot;}\" data-core-v316-plus=\"true\">\n\t\t<div class=\"elementor-element elementor-element-274f5e8 e-con-full elementor-hidden-tablet elementor-hidden-mobile e-flex e-con e-child\" data-id=\"274f5e8\" data-element_type=\"container\" data-settings=\"{&quot;content_width&quot;:&quot;full&quot;,&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-e116264 e-con-full e-flex e-con e-child\" data-id=\"e116264\" data-element_type=\"container\" data-settings=\"{&quot;content_width&quot;:&quot;full&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e42b3c4 elementor-widget__width-initial elementor-widget elementor-widget-heading\" data-id=\"e42b3c4\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Molecular <br> biomarkers<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-bf399d7 e-con-full elementor-hidden-desktop elementor-hidden-tablet e-flex e-con e-child\" data-id=\"bf399d7\" data-element_type=\"container\" data-settings=\"{&quot;content_width&quot;:&quot;full&quot;,&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2d54f8e elementor-tabs-view-horizontal elementor-widget elementor-widget-tabs\" data-id=\"2d54f8e\" data-element_type=\"widget\" data-widget_type=\"tabs.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-tabs\">\n\t\t\t<div class=\"elementor-tabs-wrapper\" role=\"tablist\" >\n\t\t\t\t\t\t\t\t\t<div id=\"elementor-tab-title-4751\" class=\"elementor-tab-title elementor-tab-desktop-title\" aria-selected=\"true\" data-tab=\"1\" role=\"tab\" tabindex=\"0\" aria-controls=\"elementor-tab-content-4751\" aria-expanded=\"false\">PET<\/div>\n\t\t\t\t\t\t\t\t\t<div id=\"elementor-tab-title-4752\" class=\"elementor-tab-title elementor-tab-desktop-title\" aria-selected=\"false\" data-tab=\"2\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-4752\" aria-expanded=\"false\">Biofluid markers<\/div>\n\t\t\t\t\t\t\t\t\t<div id=\"elementor-tab-title-4753\" class=\"elementor-tab-title elementor-tab-desktop-title\" aria-selected=\"false\" data-tab=\"3\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-4753\" aria-expanded=\"false\">Omics<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t<div class=\"elementor-tabs-content-wrapper\" role=\"tablist\" aria-orientation=\"vertical\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-tab-title elementor-tab-mobile-title\" aria-selected=\"true\" data-tab=\"1\" role=\"tab\" tabindex=\"0\" aria-controls=\"elementor-tab-content-4751\" aria-expanded=\"false\">PET<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-4751\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"1\" role=\"tabpanel\" aria-labelledby=\"elementor-tab-title-4751\" tabindex=\"0\" hidden=\"false\"><p>We are working with different PET tracers that quantify amyloid and tau burden as well as glucose metabolism in the brain.<\/p><\/div>\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-tab-title elementor-tab-mobile-title\" aria-selected=\"false\" data-tab=\"2\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-4752\" aria-expanded=\"false\">Biofluid markers<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-4752\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"2\" role=\"tabpanel\" aria-labelledby=\"elementor-tab-title-4752\" tabindex=\"0\" hidden=\"hidden\"><p>We analyze many different biomarkers of Alzheimer&#8217;s and Lewy Body diseases, neurodegeneration, neuroinflammation and synaptic dysfunction. These biomarkers are derived from the analysis of the cerebrospinal fluid and blood plasma.<\/p><\/div>\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-tab-title elementor-tab-mobile-title\" aria-selected=\"false\" data-tab=\"3\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-4753\" aria-expanded=\"false\">Omics<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-4753\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"3\" role=\"tabpanel\" aria-labelledby=\"elementor-tab-title-4753\" tabindex=\"0\" hidden=\"hidden\"><p>We conduct transcriptomic association analyses to relate brain connectome properties with the transcriptomic profiles of specific genes. This allows us to understand the genetic contribution to different connectivity patterns.<\/p><\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-6504629 e-con-full elementor-hidden-desktop elementor-hidden-tablet e-flex e-con e-parent\" data-id=\"6504629\" data-element_type=\"container\" data-settings=\"{&quot;content_width&quot;:&quot;full&quot;,&quot;background_background&quot;:&quot;classic&quot;}\" data-core-v316-plus=\"true\">\n\t\t<div class=\"elementor-element elementor-element-7189d7f e-con-full e-flex e-con e-child\" data-id=\"7189d7f\" data-element_type=\"container\" data-settings=\"{&quot;content_width&quot;:&quot;full&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-b990e15 elementor-widget elementor-widget-heading\" data-id=\"b990e15\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Recent  <br> publications<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-d325443 e-con-full e-flex e-con e-child\" data-id=\"d325443\" data-element_type=\"container\" data-settings=\"{&quot;content_width&quot;:&quot;full&quot;,&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-0f74f0c elementor-button-warning elementor-align-center elementor-widget__width-auto elementor-widget elementor-widget-button\" data-id=\"0f74f0c\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-md elementor-animation-shrink\" href=\"https:\/\/joanabpereiralab.com\/index.php\/publications\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-text\"><\/span>\n\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-b816bea e-con-full elementor-hidden-tablet elementor-hidden-mobile e-flex e-con e-parent\" data-id=\"b816bea\" data-element_type=\"container\" data-settings=\"{&quot;content_width&quot;:&quot;full&quot;,&quot;background_background&quot;:&quot;classic&quot;}\" data-core-v316-plus=\"true\">\n\t\t<div class=\"elementor-element elementor-element-3ddea46 e-con-full e-flex e-con e-child\" data-id=\"3ddea46\" data-element_type=\"container\" data-settings=\"{&quot;content_width&quot;:&quot;full&quot;,&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-34d7e16 elementor-button-warning elementor-align-center elementor-widget__width-auto elementor-widget elementor-widget-button\" data-id=\"34d7e16\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-md elementor-animation-shrink\" href=\"https:\/\/joanabpereiralab.com\/index.php\/publications\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-text\"><\/span>\n\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-253a0a5 e-con-full e-flex e-con e-child\" data-id=\"253a0a5\" data-element_type=\"container\" data-settings=\"{&quot;content_width&quot;:&quot;full&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-a319a16 elementor-widget elementor-widget-heading\" data-id=\"a319a16\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Recent  <br> publications<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>OUR RESEARCH OUR LINES Brain Aging Neurodegenerative disorders Psychiatric disorders Brain Aging Aging is one of the strongest risk factors for the development of neurodegenerative disorders. Our aim is to understand the physiological processes that occur over the the course of aging that hold important clues regarding why some individuals develop a neurodegenerative disease. Neurodegenerative &hellip;<\/p>\n<p class=\"read-more\"> <a class=\"\" href=\"https:\/\/joanabpereiralab.com\/index.php\/research\/\"> <span class=\"screen-reader-text\">RESEARCH<\/span> Read More &raquo;<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"full-width-container","site-content-style":"unboxed","site-sidebar-style":"unboxed","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"disabled","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","theme-transparent-header-meta":"enabled","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"acf":[],"rttpg_featured_image_url":null,"rttpg_author":{"display_name":"joanabpereiralab.com","author_link":"https:\/\/joanabpereiralab.com\/index.php\/author\/joanabpereiralab-com\/"},"rttpg_comment":0,"rttpg_category":null,"rttpg_excerpt":"OUR RESEARCH OUR LINES Brain Aging Neurodegenerative disorders Psychiatric disorders Brain Aging Aging is one of the strongest risk factors for the development of neurodegenerative disorders. Our aim is to understand the physiological processes that occur over the the course of aging that hold important clues regarding why some individuals develop a neurodegenerative disease. Neurodegenerative&hellip;","_links":{"self":[{"href":"https:\/\/joanabpereiralab.com\/index.php\/wp-json\/wp\/v2\/pages\/15"}],"collection":[{"href":"https:\/\/joanabpereiralab.com\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/joanabpereiralab.com\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/joanabpereiralab.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/joanabpereiralab.com\/index.php\/wp-json\/wp\/v2\/comments?post=15"}],"version-history":[{"count":326,"href":"https:\/\/joanabpereiralab.com\/index.php\/wp-json\/wp\/v2\/pages\/15\/revisions"}],"predecessor-version":[{"id":4481,"href":"https:\/\/joanabpereiralab.com\/index.php\/wp-json\/wp\/v2\/pages\/15\/revisions\/4481"}],"wp:attachment":[{"href":"https:\/\/joanabpereiralab.com\/index.php\/wp-json\/wp\/v2\/media?parent=15"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}